Protein: SEPT5
Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1)

Gene: SEPT5, SEPTIN5
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q99719

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005198 - structural molecule activity
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0005940 - septin ring

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1137003

SEPT2
Septin-2

9

19

Small-scale

0.979

High

1121195

SEPT6
Septin-6

7

19

Small-scale

0.973

High

1361605

SEPT1
Septin-1

7

19

High-throughput

0.971

High

1406708

SEP11
Septin-11

7

20

Small-scale

0.968

High

1315275

SEP12
Septin-12

7

20

High-throughput

0.963

High

1156411

SEPT7
Septin-7

5

20

Small-scale

0.930

High

1365285

SEPT8
Septin-8

5

19

Small-scale

0.929

High

1406710

SEP10
Septin-10

4

20

High-throughput

0.910

High

1406705

SEPT5
Septin-5

4

20

Small-scale

0.895

High

1406711

SEPT3
Neuronal-specific septin-3

4

20

High-throughput

0.892

High

1256419

SEP14
Septin-14

1

20

High-throughput

0.691

High

1406712

SEPT9
Septin-9

1

20

High-throughput

0.691

High

1406706

BORG4
Cdc42 effector protein 4

4

14

High-throughput

0.691

High

242705

PRKN
E3 ubiquitin-protein ligase parkin

5

11

Small-scale

0.658

High

422970

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.611

High

210504

SEPT4
Septin-4

1

20

Small-scale

0.590

High

914721

RM12
Large ribosomal subunit protein bL12m

2

9

High-throughput

0.574

High

396795

ESR1
Estrogen receptor

2

12

High-throughput

0.571

High

1386867

DDT4L
DNA damage-inducible transcript 4-like protein

2

2

High-throughput

0.553

High

762485

PROF2
Profilin-2

1

1

High-throughput

0.541

High

158301

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.536

High

530275

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.536

High

773613

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.536

High

906920

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.536

High

1142261

CD5R1
Cyclin-dependent kinase 5 activator 1

1

2

Small-scale

0.527

High

1406713

KDIS
Kinase D-interacting substrate of 220 kDa

1

1

Small-scale

0.512

High

332036

KAT7
Histone acetyltransferase KAT7

1

1

High-throughput

0.494

High

1399433

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.489

High

374159

RASN
GTPase NRas

1

20

High-throughput

0.479

High

374876

RASH
GTPase HRas

1

19

High-throughput

0.479

High

375875

RASK
GTPase KRas

1

20

High-throughput

0.479

High

541655

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

648643

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

791656

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

1087258

STX4
Syntaxin-4

1

5

Small-scale

0.479

High

278415

NCOR1
Nuclear receptor corepressor 1

1

1

High-throughput

0.470

High

344567

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.464

High

1161196

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.464

High

1406707

PKHF2
Pleckstrin homology domain-containing family F member 2

1

6

High-throughput

0.464

High

414487

P53
Cellular tumor antigen p53

1

1

High-throughput

0.445

High

954404

SNP25
Synaptosomal-associated protein 25

1

3

Small-scale

0.445

High

1014952

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.445

High

106537

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

959644

MAX
Protein max

1

3

High-throughput

0.437

High

1115025

CUL4A
Cullin-4A

1

2

High-throughput

0.437

High

1255227

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1056928

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.417

High

935044

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.407

High

848213

MAGA2
Melanoma-associated antigen 2

3

0

High-throughput

0.348

High

1406709

SPG21
Maspardin

2

0

High-throughput

0.316

High

581791

MYOG
Myogenin

1

0

High-throughput

0.282

High

1292335

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1326049

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025