Protein: SEPT4
Septin-4 (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Peanut-like protein 2)

Gene: SEPT4, SEPTIN4
Organism: Homo sapiens
Interactions: 39
UniProt ID: O43236

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001764 - neuron migration
GO:0003924 - GTPase activity
GO:0005198 - structural molecule activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210500

SEP12
Septin-12

5

20

Small-scale

0.923

High

210493

SEPT6
Septin-6

3

20

High-throughput

0.861

High

210501

SEPT1
Septin-1

3

20

High-throughput

0.861

High

210508

SEPT3
Neuronal-specific septin-3

3

20

High-throughput

0.861

High

210495

SEPT7
Septin-7

3

20

High-throughput

0.855

High

210494

SEPT2
Septin-2

2

20

High-throughput

0.811

High

210507

SEP10
Septin-10

2

20

High-throughput

0.811

High

210506

SEP11
Septin-11

2

20

High-throughput

0.776

High

210489

XIAP
E3 ubiquitin-protein ligase XIAP

6

5

Small-scale

0.745

High

210505

BORG4
Cdc42 effector protein 4

4

15

High-throughput

0.683

High

210485

SYUA
Alpha-synuclein

3

7

Small-scale

0.646

High

210475

SEPT4
Septin-4

1

20

Small-scale

0.590

High

210498

SEP14
Septin-14

1

20

Small-scale

0.590

High

210502

SEPT8
Septin-8

1

20

Small-scale

0.590

High

210504

SEPT5
Septin-5

1

20

Small-scale

0.590

High

175457

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

1

3

Small-scale

0.561

High

210481

BCL2
Apoptosis regulator Bcl-2

1

1

Small-scale

0.552

High

210487

TSC2
Tuberin

1

1

High-throughput

0.541

High

210477

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

210486

HD
Huntingtin

1

8

High-throughput

0.515

High

210488

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.515

High

210503

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.515

High

210499

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

Small-scale

0.512

High

104877

APRIO
Alternative prion protein

1

8

High-throughput

0.479

High

131592

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

Small-scale

0.479

High

210479

PARP1
Poly [ADP-ribose] polymerase 1

1

5

Small-scale

0.479

High

210480

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

Small-scale

0.479

High

210483

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

1

Small-scale

0.479

High

210484

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

10

High-throughput

0.479

High

210491

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

Small-scale

0.479

High

210492

CUL4A
Cullin-4A

1

2

High-throughput

0.479

High

210497

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

Small-scale

0.479

High

210509

TNIK
TRAF2 and NCK-interacting protein kinase

1

4

High-throughput

0.479

High

210476

NUD14
Uridine diphosphate glucose pyrophosphatase NUDT14

1

0

High-throughput

0.458

High

210478

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.458

High

210496

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

High-throughput

0.458

High

210490

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.457

High

210482

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High


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Last updated: 11Aug2025