HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 184
+	Hs
		793257 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		793262 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		349176 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		349952 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		506368 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RALA_HUMAN (4-168): 2.03e-54: 173: 51.52
+	Hs
		348560 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89
+	Hs
		350572 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		349305 CD166_HUMAN (13-607): 2.71e-98: 314: 22.33		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350155 CD166_HUMAN (13-607): 2.71e-98: 314: 22.33		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		349096 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		349841 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348489 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89
+	Hs
		349286 PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350138 PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348643 PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89
+	Hs
		914281 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		925521 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		349572 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350455 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348867 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89