HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 1088
+	Hs
		325854 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325829 TITIN_HUMAN (50-634): 4.44e-11: 68.6: 11.22		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		793321 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		793347 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MRCKA_HUMAN (656-1007): 6.11e-76: 277: 41.23
+	Hs
		530144 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		793543 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MRCKB_HUMAN (658-1007): 1.11e-70: 261: 40.34
+	Hs
		793302 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		ROCK1_HUMAN (640-1008): 1.28e-70: 260: 38.77
+	Hs
		254456 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		ROCK2_HUMAN (640-1008): 6.33e-67: 248: 36.90
+	Rn
		530226 NCAM1_RAT (11-644): 2.13e-86: 290: 15.78		ROCK1_RAT (640-1008): 4.11e-70: 258: 38.77
+	Hs
		1264826 TITIN_HUMAN (50-634): 4.44e-11: 68.6: 11.22		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30