HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21723381
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 494
+	Hs
		794468 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50
+	Hs
		794467 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		SRSF9_HUMAN (3-216): 2.37e-52: 178: 36.53
+	Hs
		1061088 RMXL1_HUMAN (1-358): 3.52e-39: 145: 93.58		SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42
+	Hs
		1099470 RMXL1_HUMAN (1-358): 3.52e-39: 145: 93.58		SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50
+	Hs
		1062075 RMXL1_HUMAN (1-358): 3.52e-39: 145: 93.58		SRSF4_HUMAN (1-468): 4.58e-48: 174: 100.00
+	Hs
		1099602 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50
+	Hs
		1099053 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF9_HUMAN (3-216): 2.37e-52: 178: 36.53
+	Mm
		915314 TIA1_MOUSE (2-367): 1.43e-26: 111: 14.70		SRSF1_MOUSE (3-166): 2.37e-57: 192: 41.42
+	Mm
		915298 TIA1_MOUSE (2-367): 1.43e-26: 111: 14.70		Q542V3_MOUSE (1-468): 2.03e-54: 191: 80.38
+	Hs
		1062152 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF4_HUMAN (1-468): 4.58e-48: 174: 100.00
+	Hs
		1060952 ELAV2_HUMAN (10-91): 2.33e-25: 107: 29.27		SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42
+	Hs
		1099306 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85
+	Hs
		1090214 ELAV2_HUMAN (10-91): 2.33e-25: 107: 29.27		SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50
+	Hs
		550154 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50
+	Hs
		550522 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50
+	Hs
		550137 TIA1_HUMAN (2-367): 1.11e-26: 111: 12.83		PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50
+	Mm
		710979 TIA1_MOUSE (2-367): 1.43e-26: 111: 14.70		PABP1_MOUSE (1-189): 6.5e-31: 128: 19.50
+	Hs
		550250 ELAV2_HUMAN (10-91): 2.33e-25: 107: 29.27		PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50
+	Hs
		726752 TIA1_HUMAN (2-367): 1.11e-26: 111: 12.83		TIAR_HUMAN (96-188): 1.12e-09: 61.9: 16.67
+	Hs
		726735 TIA1_HUMAN (2-367): 1.11e-26: 111: 12.83		TIA1_HUMAN (98-188): 2.65e-09: 61.2: 17.02