HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: RBY1F (Q15415)
RNA-binding motif protein, Y chromosome, family 1 member F/J (Y chromosome RNA recognition motif 2)
Gene: RBMY1F

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0048026 - positive regulation of mRNA splicing, via spliceosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 496
+	Hs
		515831 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RBY1A_HUMAN (1-496): 7.43e-66: 222: 99.19
+	Hs
		65203 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RBY1E_HUMAN (1-496): 1.34e-65: 221: 98.79
+	Hs
		515830 RBY1A_HUMAN (1-388): 6.35e-34: 133: 49.74		RBY1A_HUMAN (1-496): 7.43e-66: 222: 99.19
+	Hs
		515840 RBY1A_HUMAN (1-388): 6.35e-34: 133: 49.74		RBY1F_HUMAN (1-496): 1.01e-65: 222: 100.00
+	Hs
		794497 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		SAFB1_HUMAN (7-490): 3.71e-43: 165: 15.99
+	Hs
		794481 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		SAFB2_HUMAN (6-489): 8.33e-39: 152: 12.82
+	Hs
		794442 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RBM3_HUMAN (4-90): 1.64e-25: 104: 50.00
+	Hs
		794479 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		CIRBP_HUMAN (4-146): 1.26e-24: 102: 40.14
+	Hs
		794393 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RBMX_HUMAN (163-474): 7.57e-21: 96.1: 31.43
+	Hs
		284744 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RMXL2_HUMAN (242-479): 4.1e-19: 91.1: 28.69
+	Hs
		794578 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		RMXL1_HUMAN (236-465): 4.71e-17: 84.9: 38.36
+	Hs
		515837 RBY1A_HUMAN (1-388): 6.35e-34: 133: 49.74		RBM3_HUMAN (4-90): 1.64e-25: 104: 50.00
+	Hs
		550154 RBMX_HUMAN (1-367): 9.32e-45: 160: 100.00		PABP1_HUMAN (6-96): 8.45e-14: 75.7: 27.17
+	Hs
		515838 RBY1A_HUMAN (1-388): 6.35e-34: 133: 49.74		CIRBP_HUMAN (4-146): 1.26e-24: 102: 40.14
+	Hs
		284763 RMXL2_HUMAN (1-391): 3.84e-39: 145: 69.44		RMXL1_HUMAN (236-465): 4.71e-17: 84.9: 38.36