HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (EC 3.6.1.-) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1863 Hs			1 548
+	Hs
		799437 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		798841 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		798833 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		798859 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		610554 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		899159 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		1364226 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		882067 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		876094 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		899504 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		610803 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		899087 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		876074 MCPH1_HUMAN (1150-1857): 1.33e-95: 331: 14.19		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		1231188 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		881977 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		623189 RO52_HUMAN (15-390): 5.97e-69: 243: 12.86		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		876016 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		899435 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		610714 TRI68_HUMAN (12-388): 5.88e-75: 260: 11.31		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		623201 RO52_HUMAN (15-390): 5.97e-69: 243: 12.86		TCPD_HUMAN (19-525): 0: 530: 28.24