HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35182466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 3159
+	Hs
		229335 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		658639 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Mm
		570299 GATA1_MOUSE (52-419): 4.58e-38: 144: 32.88		SMCA5_MOUSE (964-1548): 0: 630: 21.32
+	Hs
		799010 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Sc
		603319 GZF3_YEAST (190-410): 6.23e-21: 97.3: 22.17		SNF2_YEAST (1515-2351): 4.31e-164: 558: 14.58
+	Hs
		799024 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		798805 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		798806 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Mm
		994722 GATA4_MOUSE (1-442): 2.77e-78: 251: 86.43		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		620435 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		620313 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		620314 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		554419 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		554420 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		620584 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Mm
		570292 GATA1_MOUSE (52-419): 4.58e-38: 144: 32.88		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		620468 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65