HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: PPR18 (Q6NYC8)
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)
Gene: PPP1R18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 613
+	Hs
		799211 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		NIPBL_HUMAN (25-436): 9.57e-61: 221: 17.78
+	Hs
		799116 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MDC1_HUMAN (15-599): 3.34e-18: 91.2: 8.86
+	Hs
		799337 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TITIN_HUMAN (39-550): 4.6e-09: 62: 10.17
+	Hs
		1129668 TOPB1_HUMAN (1122-1861): 4.09e-150: 505: 14.12		MDC1_HUMAN (15-599): 3.34e-18: 91.2: 8.86
+	Hs
		572030 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		PPR18_HUMAN (1-613): 8.37e-74: 249: 100.00
+	Hs
		572271 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		MAGL2_HUMAN (1-565): 1.29e-09: 63.5: 9.71
+	Hs
		572149 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		PRAM_HUMAN (39-539): 8.27e-09: 60.4: 10.45
+	Hs
		1129715 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		MDC1_HUMAN (15-599): 3.34e-18: 91.2: 8.86