HitPredict

Interactor 1: VATA (P38606)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)
Gene: ATP6V1A

Interactor 2: VA0D1 (P61421)
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Gene: ATP6V0D1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 35271311, 37831778
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016020 - membrane
and 8 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 617
Hs

1 351
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025