Protein: VA0D1
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)

Gene: VA0D1, ATP6V0D1
Organism: Homo sapiens
Interactions: 136
UniProt ID: P61421

Gene Ontology (top 5):
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0006879 - intracellular iron ion homeostasis
GO:0007034 - vacuolar transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292606

RENR
Renin receptor

8

2

High-throughput

0.966

High

961557

VPP1
V-type proton ATPase 116 kDa subunit a 1

5

14

High-throughput

0.919

High

961587

VPP2
V-type proton ATPase 116 kDa subunit a 2

4

14

High-throughput

0.892

High

692188

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

3

2

High-throughput

0.861

High

961524

VAS1
V-type proton ATPase subunit S1

3

2

High-throughput

0.861

High

961526

VATF
V-type proton ATPase subunit F

3

3

High-throughput

0.861

High

961588

VATD
V-type proton ATPase subunit D

2

1

High-throughput

0.811

High

637097

VATC1
V-type proton ATPase subunit C 1

2

3

High-throughput

0.789

High

961516

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

14

High-throughput

0.789

High

961562

VMA22
Vacuolar ATPase assembly protein VMA22

2

1

High-throughput

0.789

High

961545

VA0D2
V-type proton ATPase subunit d 2

2

0

High-throughput

0.748

High

961571

VPP4
V-type proton ATPase 116 kDa subunit a 4

2

14

High-throughput

0.737

High

961540

K2013
Uncharacterized protein KIAA2013

3

2

High-throughput

0.650

High

901164

RAB7A
Ras-related protein Rab-7a

2

1

High-throughput

0.628

High

171431

S27A2
Long-chain fatty acid transport protein 2

2

1

High-throughput

0.611

High

507141

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

3

High-throughput

0.611

High

637010

VATB2
V-type proton ATPase subunit B, brain isoform

2

5

Small-scale

0.611

High

800474

VATA
V-type proton ATPase catalytic subunit A

2

7

Small-scale

0.611

High

961542

VMA12
Vacuolar ATPase assembly protein VMA12

2

2

High-throughput

0.611

High

961566

SNX25
Sorting nexin-25

2

1

High-throughput

0.611

High

961584

LTOR2
Ragulator complex protein LAMTOR2

2

0

Small-scale

0.602

High

529493

TAU
Microtubule-associated protein tau

3

2

Small-scale

0.587

High

249450

ACSL4
Long-chain-fatty-acid--CoA ligase 4

2

0

High-throughput

0.585

High

648274

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

2

0

High-throughput

0.585

High

961522

DHC24
Delta(24)-sterol reductase

2

0

High-throughput

0.585

High

961531

MFS4B
Sodium-dependent glucose transporter 1

2

0

High-throughput

0.585

High

961561

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.585

High

241276

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

583072

VATB1
V-type proton ATPase subunit B, kidney isoform

2

5

High-throughput

0.584

High

961550

VATC2
V-type proton ATPase subunit C 2

1

3

High-throughput

0.575

High

395804

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

50094

S22AN
Solute carrier family 22 member 23

2

1

High-throughput

0.558

High

961528

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

1

High-throughput

0.558

High

961554

SNX19
Sorting nexin-19

2

1

High-throughput

0.558

High

961583

S27A6
Long-chain fatty acid transport protein 6

2

1

High-throughput

0.558

High

224961

TLX3
T-cell leukemia homeobox protein 3

2

3

High-throughput

0.553

High

276826

VATG1
V-type proton ATPase subunit G 1

1

3

High-throughput

0.536

High

784780

VATE1
V-type proton ATPase subunit E 1

1

1

High-throughput

0.536

High

961523

VAMP3
Vesicle-associated membrane protein 3

1

4

High-throughput

0.536

High

961529

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.536

High

961581

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.536

High

458360

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

843447

HD
Huntingtin

1

1

High-throughput

0.515

High

64945

ARRD5
Arrestin domain-containing protein 5

1

0

High-throughput

0.513

High

321754

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.513

High

443288

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.513

High

540387

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

611068

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.513

High

837510

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.513

High

900753

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.513

High

956234

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.513

High

961509

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

961519

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

961536

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

961537

STX12
Syntaxin-12

1

0

High-throughput

0.513

High

961547

S38A9
Neutral amino acid transporter 9

1

0

Small-scale

0.513

High

961548

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

961560

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

961567

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.513

High

961579

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.513

High

961586

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

961582

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.512

High

178234

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

507763

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

961514

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

961520

RB39A
Ras-related protein Rab-39A

1

1

High-throughput

0.479

High

961551

T185A
Transmembrane protein 185A

1

1

High-throughput

0.479

High

961564

SERC2
Serine incorporator 2

1

1

High-throughput

0.479

High

961575

S38A7
Sodium-coupled neutral amino acid transporter 7

1

2

Small-scale

0.479

High

345601

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

536881

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

961517

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

961521

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

961533

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.458

High

961538

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

961541

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

961544

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

961549

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

961580

S12A6
Solute carrier family 12 member 6

1

0

Small-scale

0.458

High

961585

UFC1
Ubiquitin-fold modifier-conjugating enzyme 1

1

0

High-throughput

0.458

High

341203

VATG2
V-type proton ATPase subunit G 2

1

3

High-throughput

0.445

High

954382

SNP25
Synaptosomal-associated protein 25

1

1

Small-scale

0.445

High

961532

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

952049

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

Small-scale

0.437

High

961515

UT1
Urea transporter 1

1

1

High-throughput

0.437

High

961555

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

961556

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.437

High

961568

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

627301

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

0

High-throughput

0.426

High

841132

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

942526

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

961543

CD177
CD177 antigen

1

0

Small-scale

0.426

High

961565

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.426

High

961563

S38A2
Sodium-coupled neutral amino acid symporter 2

1

2

High-throughput

0.407

High

927211

ATX1
Ataxin-1

2

0

High-throughput

0.327

High

187326

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

0

High-throughput

0.318

High

871468

LEPR
Leptin receptor

2

0

High-throughput

0.318

High

921499

MVD1
Diphosphomevalonate decarboxylase

2

0

High-throughput

0.318

High

961511

NTCP7
Sodium/bile acid cotransporter 7

2

0

High-throughput

0.318

High

961518

CUL4A
Cullin-4A

2

0

High-throughput

0.318

High

961569

PGES2
Prostaglandin E synthase 2

2

0

High-throughput

0.318

High

961572

M1IP1
Mid1-interacting protein 1

2

0

High-throughput

0.318

High

961576

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

0

High-throughput

0.318

High

961573

DMRT3
Doublesex- and mab-3-related transcription factor 3

2

0

High-throughput

0.316

High

588373

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.305

High

695104

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.305

High

767861

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.305

High

590402

GATA1
Erythroid transcription factor

1

0

High-throughput

0.292

High

961510

TLE5
TLE family member 5

1

0

High-throughput

0.292

High

961539

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.292

High

961558

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.292

High

329240

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

608243

EGLN
Endoglin

1

0

High-throughput

0.279

Low

724024

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

961512

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.279

Low

961513

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.279

Low

961534

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

0

High-throughput

0.279

Low

961546

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

961553

THOC2
THO complex subunit 2

1

0

High-throughput

0.279

Low

961578

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.279

Low

892656

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low

222878

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

606536

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

710154

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.249

Low

845578

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

895862

PDLI4
PDZ and LIM domain protein 4

1

0

High-throughput

0.249

Low

961525

GRIK4
Glutamate receptor ionotropic, kainate 4

1

0

High-throughput

0.249

Low

961535

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

961552

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

961559

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

961570

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

961574

ANLN
Anillin

1

0

High-throughput

0.249

Low

961577

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

961508

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.232

Low

961527

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

961530

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025