Protein: VA0D
V-type proton ATPase subunit d (V-ATPase subunit d) (V-ATPase 39 kDa subunit) (V-ATPase subunit M39) (Vacuolar proton pump subunit d)

Gene: VA0D, VMA6
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P32366

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007034 - vacuolar transport
GO:0007035 - vacuolar acidification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

735697

VPP1
V-type proton ATPase subunit a, vacuolar isoform

12

14

Small-scale

0.983

High

735709

VPP2
V-type proton ATPase subunit a, Golgi isoform

5

14

Small-scale

0.906

High

735720

VATF
V-type proton ATPase subunit F

4

3

High-throughput

0.903

High

726551

VATC
V-type proton ATPase subunit C

3

3

Small-scale

0.837

High

735716

VMA22
Vacuolar ATPase assembly protein VMA22

3

0

High-throughput

0.813

High

735699

VATD
V-type proton ATPase subunit D

2

1

High-throughput

0.793

High

735743

VOA1
V0 assembly protein 1

2

0

High-throughput

0.753

High

603430

VATA
V-type proton ATPase catalytic subunit A

5

9

Small-scale

0.712

High

592087

VATB
V-type proton ATPase subunit B

3

5

High-throughput

0.662

High

645804

VATE
V-type proton ATPase subunit E

3

1

Small-scale

0.648

High

735731

VATH
V-type proton ATPase subunit H

3

1

Small-scale

0.648

High

735740

VATG
V-type proton ATPase subunit G

3

3

Small-scale

0.646

High

735700

VATL2
V-type proton ATPase subunit c'

1

2

High-throughput

0.618

High

734793

VPH2
Vacuolar ATPase assembly integral membrane protein VPH2

2

0

Small-scale

0.576

High

735704

MTH1
Protein MTH1

1

1

High-throughput

0.494

High

735729

YAP4
AP-1-like transcription factor YAP4

1

1

High-throughput

0.494

High

735751

STD1
Protein STD1

1

1

High-throughput

0.494

High

735755

YAP6
AP-1-like transcription factor YAP6

1

1

High-throughput

0.494

High

735703

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.489

High

735741

YOR1
Oligomycin resistance ATP-dependent permease YOR1

1

2

High-throughput

0.489

High

575720

BPT1
Bile pigment transporter 1

1

2

High-throughput

0.479

High

673283

ADP1
Probable ATP-dependent permease

1

1

High-throughput

0.479

High

693170

PHO91
Low-affinity phosphate transporter PHO91

1

1

High-throughput

0.479

High

735695

YBT1
ATP-dependent bile acid permease

1

1

High-throughput

0.479

High

735707

AVT3
Vacuolar amino acid transporter 3

1

2

High-throughput

0.479

High

735711

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

735725

VTC1
Vacuolar transporter chaperone complex subunit 1

1

3

High-throughput

0.479

High

735728

SYG1
Protein SYG1

1

1

High-throughput

0.479

High

735732

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

1

High-throughput

0.479

High

735733

VTC2
Vacuolar transporter chaperone complex subunit 2

1

5

High-throughput

0.479

High

735737

VTC4
Vacuolar transporter chaperone complex subunit 4

1

5

High-throughput

0.479

High

735750

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

5

High-throughput

0.479

High

735754

RMD1
Sporulation protein RMD1

1

1

High-throughput

0.479

High

735759

CSC1
Calcium permeable stress-gated cation channel 1

1

1

High-throughput

0.479

High

735768

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

1

High-throughput

0.479

High

735770

NYV1
Vacuolar v-SNARE NYV1

1

4

High-throughput

0.479

High

735774

YPK9
Vacuolar cation-transporting ATPase YPK9

1

1

High-throughput

0.479

High

735775

VCX1
Vacuolar calcium ion transporter

1

1

High-throughput

0.479

High

547033

PPB
Repressible alkaline phosphatase

1

0

High-throughput

0.458

High

735698

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

735712

PFF1
Vacuolar membrane protease

1

0

High-throughput

0.458

High

735717

VTC5
Vacuole transporter chaperone complex subunit 5

1

0

High-throughput

0.458

High

735723

KC13
Casein kinase I homolog 3

1

0

High-throughput

0.458

High

735724

VAC8
Vacuolar protein 8

1

0

High-throughput

0.458

High

735744

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.458

High

735764

SMF3
Iron transporter SMF3

1

0

High-throughput

0.458

High

735766

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

735771

YVC1
Calcium channel YVC1

1

0

High-throughput

0.458

High

735761

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

1

Small-scale

0.445

High

735718

TEM1
Protein TEM1

1

2

High-throughput

0.437

High

735734

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

735735

RMD8
Sporulation protein RMD8

1

1

High-throughput

0.437

High

735701

PTM1
Membrane protein PTM1

1

0

High-throughput

0.426

High

735719

HXT7
High-affinity hexose transporter HXT7

1

1

High-throughput

0.407

High

735727

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

735730

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

4

0

Small-scale

0.359

High

726830

HS104
Heat shock protein 104

2

0

High-throughput

0.305

High

735773

CMR1
DNA damage-binding protein CMR1

2

0

High-throughput

0.305

High

735706

MAOM
NAD-dependent malic enzyme, mitochondrial

2

0

High-throughput

0.293

High

735739

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.282

High

735745

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

735746

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.279

Low

735749

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.279

Low

735753

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.279

Low

735758

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.279

Low

735760

OMS1
Methyltransferase OMS1, mitochondrial

1

0

High-throughput

0.279

Low

735772

LAS17
Proline-rich protein LAS17

1

0

High-throughput

0.279

Low

735721

ATC3
Phospholipid-transporting ATPase DRS2

1

0

High-throughput

0.269

Low

464572

PBS2
MAP kinase kinase PBS2

1

0

High-throughput

0.249

Low

646338

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

670453

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

694113

CDC15
Cell division control protein 15

1

0

High-throughput

0.249

Low

705142

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

706474

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709619

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

734880

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

735696

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

735705

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

735708

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

735710

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

735715

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

735722

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

735726

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.249

Low

735736

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

735738

YJ09
Uncharacterized protein YJR039W

1

0

High-throughput

0.249

Low

735742

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

735747

H3
Histone H3

1

0

High-throughput

0.249

Low

735748

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

735752

ESP1
Separin

1

0

High-throughput

0.249

Low

735756

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

735762

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

735763

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

735765

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

735767

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

659331

MRS4
Mitochondrial RNA-splicing protein MRS4

1

0

High-throughput

0.232

Low

735702

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.232

Low

735713

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.232

Low

735714

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

735757

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.232

Low

735769

NCE2
Non-classical export protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025