HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 26949251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 486
+	Hs
		801197 KI67_HUMAN (1-3256): 0: 1046: 100.00		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06
+	Mm
		1207240 SRRM2_MOUSE (40-2336): 3.29e-40: 167: 7.61		MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44
+	Mm
		957037 RBBP6_MOUSE (2526-3195): 1.91e-12: 75.9: 13.43		MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44
+	Hs
		328680 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		1264771 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		TITIN_HUMAN (240-472): 1.28e-12: 72.8: 19.57
+	Hs
		1154038 NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06