HitPredict

Interactor 1: HSPA9 (P38646)
Stress-70 protein, mitochondrial (EC 3.6.4.10) (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: ACON (Q99798)
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
Gene: ACO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 31839598
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 679 Hs			1 780
+	Hs
		537781 HSP7C_HUMAN (51-653): 0: 882: 50.16		ACON_HUMAN (1-780): 0: 1062: 100.00
+	Sc
		510175 HSP77_YEAST (37-653): 0: 785: 66.61		ACON_YEAST (9-780): 0: 1024: 66.24
+	At
		653942 HS701_ARATH (48-673): 0: 876: 48.24		ACO2M_ARATH (4-775): 0: 843: 25.06
+	Hs
		536490 HSP7C_HUMAN (51-653): 0: 882: 50.16		ACOHC_HUMAN (24-780): 0: 818: 25.08
+	Sc
		510502 HSP77_YEAST (37-653): 0: 785: 66.61		ACON2_YEAST (18-780): 0: 888: 53.00
+	Hs
		535453 BIP_HUMAN (53-677): 0: 566: 50.55		ACON_HUMAN (1-780): 0: 1062: 100.00
+	At
		1443086 HSP7G_ARATH (55-654): 0: 605: 53.32		ACO3M_ARATH (3-780): 0: 862: 25.19
+	Sc
		510642 HSP77_YEAST (37-653): 0: 785: 66.61		LYS4_YEAST (61-711): 1.7e-165: 496: 23.74
+	Ec
		489268 DNAK_ECOLI (53-673): 0: 690: 60.22		LEUC_ECOLI (62-507): 5.9e-149: 445: 23.22
+	Sc
		881821 HSP7Q_YEAST (55-658): 0: 567: 49.53		LYS4_YEAST (61-711): 1.7e-165: 496: 23.74
+	Ec
		491170 DNAK_ECOLI (53-673): 0: 690: 60.22		LEUD_ECOLI (580-769): 5.23e-48: 170: 17.90