HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: STF1 (Q13285)
Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP)
Gene: NR5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 461
+	Hs
		924542 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		209047 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		1030589 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		557679 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		824471 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		NR2C2_HUMAN (11-457): 1.94e-116: 355: 21.80
+	Hs
		824589 CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12		NR2C2_HUMAN (11-457): 1.94e-116: 355: 21.80
+	Hs
		369863 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		320200 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		ERR2_HUMAN (2-166): 2.54e-54: 189: 40.72
+	Hs
		370679 VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		370586 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		370817 CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90