Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 25416956, 26496610, 24981174, 27193484, 31904842, 32645369, 35271311, 26186194, 26508657, 28514442, 33961781, 36563124, 31515488, 32814053, 14667819
Identification Methods two hybrid, affinity chromatography technology, biochemical, pull down, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~zf-RING_2, ubiquitin~zinc_ribbon_9
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1132
Hs

1 311
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Last updated: 15 Jul 2024