HitPredict

Interactor 1: ZIC1 (P46684)
Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1)
Gene: ZIC1

Interactor 2: Q8K0K3 (Q8K0K3)
Gli2 protein
Gene: Gli2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	11238441
Identification Methods	anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 447 Mm			1 538
+	Mm
		101488 F8VPV3_MOUSE (1-424): 5.89e-166: 479: 67.40		GLI2_MOUSE (1-538): 2.73e-141: 446: 100.00
+	Mm
		1143984 ZIC2_MOUSE (1-424): 5.18e-164: 474: 67.25		Q8K0K3_MOUSE (1-538): 3.65e-118: 361: 100.00
+	Hs
		485068 ZIC1_HUMAN (1-447): 3.42e-140: 410: 99.33		GLI2_HUMAN (1-538): 5.16e-119: 386: 70.32
+	Hs
		485122 ZIC1_HUMAN (1-447): 3.42e-140: 410: 99.33		GLI3_HUMAN (5-537): 2.31e-99: 330: 28.91
+	Hs
		234699 ZIC3_HUMAN (1-447): 3.92e-116: 350: 61.73		GLI3_HUMAN (5-537): 2.31e-99: 330: 28.91
+	Hs
		436717 ZIC1_HUMAN (1-447): 3.42e-140: 410: 99.33		GLI1_HUMAN (48-535): 1.59e-42: 164: 16.50
+	Hs
		485039 GLI2_HUMAN (240-382): 6.8e-39: 152: 54.11		GLI3_HUMAN (5-537): 2.31e-99: 330: 28.91
+	Hs
		313636 ZIC2_HUMAN (339-445): 1.07e-13: 75: 17.24		GLI2_HUMAN (1-538): 5.16e-119: 386: 70.32
+	Hs
		313637 ZIC2_HUMAN (339-445): 1.07e-13: 75: 17.24		GLI3_HUMAN (5-537): 2.31e-99: 330: 28.91
+	Hs
		436665 GLI3_HUMAN (240-382): 8.82e-39: 151: 53.43		GLI1_HUMAN (48-535): 1.59e-42: 164: 16.50
+	Hs
		436663 GLI1_HUMAN (242-382): 4.56e-37: 146: 53.47		GLI1_HUMAN (48-535): 1.59e-42: 164: 16.50
+	Hs
		313635 ZIC2_HUMAN (339-445): 1.07e-13: 75: 17.24		GLI1_HUMAN (48-535): 1.59e-42: 164: 16.50