HitPredict

Interactor 1: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 11805826, 16554755, 37968396, 9228276, 16429126, 17499717, 14759368
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 268
Sc

1 405
+ At
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Zm
+ Dm
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025