HitPredict

Interactor 1: BRCA1 (B6VQ60)
Breast cancer type 1 susceptibility protein homolog (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1)
Gene: brc-1

Interactor 2: BARD1 (Q21209)
BRCA1-associated RING domain protein 1 (BARD1) (Ce-BRD-1) (Cebrd-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: brd-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.661

The method score is based on:

Property Details
Experiments 14711411, 30650366, 14704431
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005694 - chromosome
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
and 5 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 612
Ce

1 702
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024