HitPredict

Interactor 1: AURK (P38991)
Aurora kinase (EC 2.7.11.1) (Increase-in-ploidy protein 1) (Spindle assembly checkpoint kinase)
Gene: IPL1

Interactor 2: AURK (P38991)
Aurora kinase (EC 2.7.11.1) (Increase-in-ploidy protein 1) (Spindle assembly checkpoint kinase)
Gene: IPL1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 31112132, 23454383
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 26 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 367
Sc

1 367
+ Mm
+ At
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+ At
+ At
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025