HitPredict

Interactor 1: RV167 (P39743)
Reduced viability upon starvation protein 167
Gene: RVS167

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	10512884, 11489916, 7719850, 10688190, 11096097
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0015629 - actin cytoskeleton GO:0030479 - actin cortical patch
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 482 Sc			1 375
+	Hs
		952816 SRC8_HUMAN (15-481): 7.2e-52: 186: 15.01		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		993176 SRC8_HUMAN (15-481): 7.2e-52: 186: 15.01		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		138475 BIN1_HUMAN (3-481): 2.05e-50: 183: 12.00		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		1154094 ITSN1_HUMAN (192-482): 9.76e-20: 94.9: 16.67		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		993383 PACN2_HUMAN (5-481): 5.31e-51: 182: 15.48		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		995590 SRC8_HUMAN (15-481): 7.2e-52: 186: 15.01		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		138477 BIN1_HUMAN (3-481): 2.05e-50: 183: 12.00		ACTS_HUMAN (2-375): 0: 590: 86.90
+	Ce
		73277 SH3GH_CAEEL (75-479): 1.99e-46: 167: 18.43		ACT4_CAEEL (2-375): 0: 598: 89.04
+	Sc
		948648 MYO5_YEAST (6-479): 7.5e-43: 164: 11.07		ACT_YEAST (1-375): 0: 594: 100.00
+	Hs
		993310 SH3G2_HUMAN (84-480): 1.27e-41: 153: 14.25		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Sc
		745030 YSC84_YEAST (384-480): 7.31e-28: 117: 30.93		ACT_YEAST (1-375): 0: 594: 100.00
+	Hs
		952844 ITSN1_HUMAN (192-482): 9.76e-20: 94.9: 16.67		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		993189 ITSN1_HUMAN (192-482): 9.76e-20: 94.9: 16.67		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		996460 ITSN1_HUMAN (192-482): 9.76e-20: 94.9: 16.67		ACTS_HUMAN (2-375): 0: 590: 86.90