HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (EC 3.6.1.-) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25940091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 1335
+	Hs
		1322637 TCPH_HUMAN (2-530): 0: 576: 27.93		RPTOR_HUMAN (1-1335): 0: 1443: 100.00
+	At
		1373205 TCPZA_ARATH (3-530): 0: 664: 62.29		RTOR1_ARATH (27-1328): 0: 1171: 40.75
+	At
		1318451 TCPZB_ARATH (3-530): 0: 655: 62.29		RTOR1_ARATH (27-1328): 0: 1171: 40.75
+	Hs
		821491 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (961-1324): 9.8e-69: 248: 14.91
+	Hs
		965190 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		821289 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		1407533 TCPH_HUMAN (2-530): 0: 576: 27.93		TBL1Y_HUMAN (1059-1334): 3.03e-54: 200: 13.54
+	Hs
		821534 TCPZ_HUMAN (1-531): 0: 573: 100.00		TBL1Y_HUMAN (1059-1334): 3.03e-54: 200: 13.54
+	Hs
		845257 TCPG_HUMAN (3-528): 0: 559: 27.96		LIS1_HUMAN (1101-1334): 1.21e-54: 198: 15.69
+	Hs
		1291941 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (1200-1334): 7.77e-30: 123: 11.77
+	Hs
		821436 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (1200-1334): 7.77e-30: 123: 11.77
+	Hs
		1048175 TCPH_HUMAN (2-530): 0: 576: 27.93		TLE4_HUMAN (1165-1335): 7.42e-23: 107: 13.07
+	Hs
		1405326 TCPH_HUMAN (2-530): 0: 576: 27.93		PI3R4_HUMAN (1102-1335): 1.55e-18: 94.5: 13.78
+	Hs
		821524 TCPZ_HUMAN (1-531): 0: 573: 100.00		PI3R4_HUMAN (1102-1335): 1.55e-18: 94.5: 13.78
+	Hs
		1407542 TCPH_HUMAN (2-530): 0: 576: 27.93		KTNB1_HUMAN (1110-1332): 6.76e-18: 91.4: 23.21
+	Hs
		1334162 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (932-1114): 1.24e-17: 89.1: 11.31
+	Hs
		821543 TCPZ_HUMAN (1-531): 0: 573: 100.00		KTNB1_HUMAN (1110-1332): 6.76e-18: 91.4: 23.21
+	Hs
		821453 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (932-1114): 1.24e-17: 89.1: 11.31
+	Sc
		811199 TCPZ_YEAST (3-530): 0: 579: 56.75		PRP46_YEAST (1076-1328): 1.97e-14: 79.5: 20.78
+	Hs
		821497 TCPZ_HUMAN (1-531): 0: 573: 100.00		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58