HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (EC 3.6.1.-) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: FBXW8 (Q8N3Y1)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29)
Gene: FBXW8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21572988
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 598
+	Hs
		1325517 TCPH_HUMAN (2-530): 0: 576: 27.93		FBXW8_HUMAN (1-598): 3.04e-130: 396: 96.17
+	Hs
		1407533 TCPH_HUMAN (2-530): 0: 576: 27.93		TBL1Y_HUMAN (22-419): 3.38e-61: 213: 10.38
+	Hs
		821534 TCPZ_HUMAN (1-531): 0: 573: 100.00		TBL1Y_HUMAN (22-419): 3.38e-61: 213: 10.38
+	Hs
		1291941 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (40-372): 3.65e-55: 191: 13.70
+	Hs
		821436 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (40-372): 3.65e-55: 191: 13.70
+	Hs
		1287302 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR86_HUMAN (102-378): 4.44e-46: 168: 13.01
+	Hs
		821431 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR86_HUMAN (102-378): 4.44e-46: 168: 13.01
+	Hs
		1334162 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (52-324): 2.63e-40: 153: 14.03
+	Hs
		845257 TCPG_HUMAN (3-528): 0: 559: 27.96		LIS1_HUMAN (4-327): 1.35e-46: 170: 10.77
+	Hs
		821453 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (52-324): 2.63e-40: 153: 14.03
+	Hs
		821491 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (417-592): 2.78e-37: 149: 16.85
+	Hs
		1407634 TCPH_HUMAN (2-530): 0: 576: 27.93		FBW1A_HUMAN (421-593): 4.84e-32: 132: 17.22
+	Hs
		821625 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBW1A_HUMAN (421-593): 4.84e-32: 132: 17.22
+	Hs
		821618 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBW1B_HUMAN (421-593): 3.1e-31: 130: 18.33
+	Hs
		1221017 TCPH_HUMAN (2-530): 0: 576: 27.93		FBW10_HUMAN (387-566): 1.88e-25: 114: 19.78
+	Hs
		1407594 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (50-235): 4.2e-19: 92.6: 13.71
+	Hs
		821597 TCPZ_HUMAN (1-531): 0: 573: 100.00		NLE1_HUMAN (50-235): 4.2e-19: 92.6: 13.71
+	Hs
		965190 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (110-238): 7.41e-12: 68.8: 9.42
+	Hs
		821289 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (110-238): 7.41e-12: 68.8: 9.42
+	Hs
		881861 TCPG_HUMAN (3-528): 0: 559: 27.96		WDR5_HUMAN (110-238): 7.41e-12: 68.8: 9.42