Interactor 1: VHL (P40338)
von Hippel-Lindau disease tumor suppressor (pVHL)
Gene: VHL
Interactor 2: HIF1A (Q61221)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)
Gene: HIF1A
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.922 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HIF-1~VHL |
| Common GO terms | GO:0001525 - angiogenesis GO:0005634 - nucleus GO:0010629 - negative regulation of gene expression GO:0048593 - camera-type eye morphogenesis GO:0061072 - iris morphogenesis and 3 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
