HitPredict

Interactor 1: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Interactor 2: NU100 (Q02629)
Nucleoporin NUP100/NSP100 (Nuclear pore protein NUP100/NSP100)
Gene: NUP100

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 11387327, 12543930, 29033133, 18046405, 17418788
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Nucleoporin2~Nucleoporin2
Common GO terms GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003723 - RNA binding
GO:0005643 - nuclear pore
GO:0006405 - RNA export from nucleus
GO:0006606 - protein import into nucleus
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1317
Sc

1 959
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Tt
+ Hs
+ Sc
+ Ce
+ Hs
+ Hs
+ Ce
+ Sc
+ Ce
+ Sc
+ Tt
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024