Interactor 1: CCNF (P41002)
Cyclin-F (F-box only protein 1)
Gene: CCNF

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 29103612, 37028429, 37831778, 28954236, 31130363, 31577344, 35231559, 35813202, 36114006, 37243816, 21640084, 23319600, 20596027, 22632967
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, interactome parallel affinity capture
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 786
Hs

1 776
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Sc

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Last updated: 11Aug2025