HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 559
+	Hs
		833715 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		834023 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		788029 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		625635 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		YETS2_HUMAN (3-502): 1.64e-35: 144: 12.96
+	Hs
		625393 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		625532 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Ce
		1094269 MBK2_CAEEL (145-487): 5.44e-111: 349: 27.93		Q21501_CAEEL (7-147): 5.18e-42: 151: 25.85
+	Hs
		999248 DYR1B_HUMAN (108-488): 2.22e-110: 342: 29.03		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		414892 CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		1270845 DYR1B_HUMAN (108-488): 2.22e-110: 342: 29.03		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Hs
		998682 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		1044010 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Hs
		1044321 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		PCLO_HUMAN (156-526): 9.46e-09: 60.9: 10.13