HitPredict

Interactor 1: SYIC (P41252)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
Gene: IARS1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1262 Hs			1 626
+	Hs
		834490 SYIC_HUMAN (1-1262): 0: 1487: 100.00		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		834500 SYIC_HUMAN (1-1262): 0: 1487: 100.00		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		834412 SYIC_HUMAN (1-1262): 0: 1487: 100.00		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		834389 SYIC_HUMAN (1-1262): 0: 1487: 100.00		LIS1_HUMAN (524-623): 3.63e-12: 70.5: 11.00
+	Sc
		481929 SYIC_YEAST (2-1071): 0: 1024: 53.02		CMR1_YEAST (159-623): 1.95e-74: 249: 23.50
+	Hs
		687870 SYVC_HUMAN (1-961): 0: 821: 18.95		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		1436816 SYLC_HUMAN (3-993): 0: 669: 16.08		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Ce
		1018629 SYIC_CAEEL (2-1077): 0: 1022: 58.06		LIN53_CAEEL (251-477): 2.76e-20: 95.7: 15.73
+	Hs
		687778 SYVC_HUMAN (1-961): 0: 821: 18.95		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		1380219 SYLC_HUMAN (3-993): 0: 669: 16.08		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Ce
		1018736 SYV_CAEEL (1-992): 0: 786: 19.43		LIN53_CAEEL (251-477): 2.76e-20: 95.7: 15.73
+	Hs
		142425 SYIM_HUMAN (3-904): 0: 692: 25.42		PEX7_HUMAN (308-524): 9.84e-31: 124: 22.02
+	Ce
		1018545 SYLC_CAEEL (1-1008): 0: 613: 15.59		LIN53_CAEEL (251-477): 2.76e-20: 95.7: 15.73