Interactor 1: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 31843895, 36779422, 24879152
Identification Methods enzymatic study, proximity labelling technology, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0003073 - regulation of systemic arterial blood pressure
GO:0003214 - cardiac left ventricle morphogenesis
GO:0004674 - protein serine/threonine kinase activity
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
and 62 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 483
Hs

1 483
+ Zm
+ At
+ At
+ At
+ Os
+ Hs
+ At
+ At
+ Hs
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024