HitPredict

Interactor 1: GDIB (P50395)
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Gene: GDI2

Interactor 2: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0015031 - protein transport GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 213
+	Hs
		838625 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05
+	Hs
		838647 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90
+	Hs
		838624 GDIB_HUMAN (1-445): 0: 722: 100.00		RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37
+	Hs
		838683 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Mm
		838709 GDIA_MOUSE (1-444): 0: 717: 87.39		RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05
+	Hs
		678344 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05
+	Hs
		678359 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90
+	Hs
		678343 GDIA_HUMAN (1-444): 0: 714: 86.49		RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37
+	Hs
		678394 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Dm
		185501 Q9VLB7_DROME (1-440): 0: 662: 67.80		O18332_DROME (1-210): 6.56e-87: 256: 40.48
+	Dm
		185708 Q9VLB7_DROME (1-440): 0: 662: 67.80		O18335_DROME (1-211): 4.17e-85: 252: 57.67
+	Hs
		838621 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB14_HUMAN (8-203): 1.14e-53: 172: 44.39
+	Hs
		678341 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB14_HUMAN (8-203): 1.14e-53: 172: 44.39
+	Sp
		568530 GDI1_SCHPO (1-439): 0: 635: 56.14		YPT3_SCHPO (6-180): 8.44e-75: 226: 64.00
+	Sc
		350882 GDI1_YEAST (1-438): 0: 606: 54.16		YPT1_YEAST (6-210): 3.3e-85: 252: 43.42
+	Sc
		750738 GDI1_YEAST (1-438): 0: 606: 54.16		YPT31_YEAST (8-203): 8.06e-72: 219: 56.85
+	Sc
		765614 GDI1_YEAST (1-438): 0: 606: 54.16		YPT32_YEAST (8-201): 8.14e-69: 211: 54.64
+	Dm
		185694 RABEP_DROME (3-445): 7.84e-136: 401: 23.09		O18335_DROME (1-211): 4.17e-85: 252: 57.67
+	Sc
		350859 RAEP_YEAST (3-374): 2.36e-120: 365: 27.50		YPT1_YEAST (6-210): 3.3e-85: 252: 43.42
+	Sc
		699423 RAEP_YEAST (3-374): 2.36e-120: 365: 27.50		YPT31_YEAST (8-203): 8.06e-72: 219: 56.85