HitPredict

Interactor 1: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tubulin~fn3
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 445
+	Hs
		841544 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		457287 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		841545 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		408001 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		841579 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		841553 I12R1_HUMAN (1-662): 3.34e-161: 480: 100.00		TBB8_HUMAN (1-427): 0: 696: 91.10
+	Hs
		522644 PTPRF_HUMAN (288-660): 2.45e-20: 98.6: 11.97		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		1102697 PTPRS_HUMAN (11-296): 1.82e-11: 69.7: 12.00		TBB2A_HUMAN (1-430): 0: 707: 97.67