Protein: I12R1
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)

Gene: I12R1, IL12RB1
Organism: Homo sapiens
Interactions: 101
UniProt ID: P42701

Gene Ontology (top 5):
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002230 - positive regulation of defense response to virus by host
GO:0002827 - positive regulation of T-helper 1 type immune response
GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

841561

TBA1A
Tubulin alpha-1A chain

2

6

High-throughput

0.789

High

408001

TBB4A
Tubulin beta-4A chain

3

8

High-throughput

0.770

High

841538

TBA4A
Tubulin alpha-4A chain

3

4

High-throughput

0.770

High

841544

TBB3
Tubulin beta-3 chain

3

8

High-throughput

0.770

High

841553

TBB8
Tubulin beta-8 chain

3

8

High-throughput

0.770

High

712742

IL12B
Interleukin-12 subunit beta

2

17

Small-scale

0.754

High

841559

CREL2
Protein disulfide isomerase CRELD2

2

8

High-throughput

0.705

High

841533

LAMB2
Laminin subunit beta-2

2

14

High-throughput

0.694

High

520772

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

3

High-throughput

0.691

High

612046

ITB5
Integrin beta-5

1

8

High-throughput

0.691

High

841541

SEM3B
Semaphorin-3B

1

3

High-throughput

0.691

High

841569

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

2

High-throughput

0.691

High

841592

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

2

High-throughput

0.691

High

841598

JAG2
Protein jagged-2

1

2

High-throughput

0.691

High

841599

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.691

High

534750

BIP
Endoplasmic reticulum chaperone BiP

3

6

High-throughput

0.667

High

712719

IL12A
Interleukin-12 subunit alpha

2

1

Small-scale

0.624

High

457287

TBB5
Tubulin beta chain

1

8

High-throughput

0.618

High

841539

TBB4B
Tubulin beta-4B chain

1

8

High-throughput

0.618

High

841545

TBB2A
Tubulin beta-2A chain

1

8

High-throughput

0.618

High

841548

GANAB
Neutral alpha-glucosidase AB

1

3

High-throughput

0.618

High

841557

POTEE
POTE ankyrin domain family member E

1

1

High-throughput

0.618

High

841577

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.618

High

841579

TBB6
Tubulin beta-6 chain

1

8

High-throughput

0.618

High

841584

TBB1
Tubulin beta-1 chain

1

9

High-throughput

0.618

High

841587

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

1

High-throughput

0.618

High

841586

IL23A
Interleukin-23 subunit alpha

1

0

Small-scale

0.614

High

841578

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

3

1

High-throughput

0.609

High

841583

TXNIP
Thioredoxin-interacting protein

3

5

High-throughput

0.609

High

841601

LOXL2
Lysyl oxidase homolog 2

3

1

High-throughput

0.609

High

452083

PROS
Vitamin K-dependent protein S

1

6

High-throughput

0.575

High

841546

GAS6
Growth arrest-specific protein 6

1

6

High-throughput

0.575

High

563371

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

841558

CSPG4
Chondroitin sulfate proteoglycan 4

1

5

High-throughput

0.536

High

841570

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

1

High-throughput

0.536

High

841575

NEUR1
Sialidase-1

1

2

High-throughput

0.536

High

841597

NEUR3
Sialidase-3

1

2

High-throughput

0.536

High

841554

IL23R
Interleukin-23 receptor

1

18

Small-scale

0.534

High

535822

LAMC1
Laminin subunit gamma-1

1

12

High-throughput

0.514

High

572681

NID1
Nidogen-1

1

1

High-throughput

0.514

High

841571

PXDN
Peroxidasin homolog

1

6

High-throughput

0.514

High

370007

TIMP1
Metalloproteinase inhibitor 1

1

0

High-throughput

0.513

High

841565

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.513

High

841576

TM9S2
Transmembrane 9 superfamily member 2

1

0

High-throughput

0.513

High

841588

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.513

High

183335

ZN185
Zinc finger protein 185

1

1

High-throughput

0.489

High

323972

CSTN1
Calsyntenin-1

1

20

High-throughput

0.489

High

335677

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

1

High-throughput

0.489

High

552156

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

653175

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.489

High

697453

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.489

High

841530

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.489

High

841542

DNJC3
DnaJ homolog subfamily C member 3

1

4

High-throughput

0.489

High

841543

OS9
Protein OS-9

1

1

High-throughput

0.489

High

841549

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

1

High-throughput

0.489

High

841550

DPOD3
DNA polymerase delta subunit 3

1

3

High-throughput

0.489

High

841552

NPTX1
Neuronal pentraxin-1

1

1

High-throughput

0.489

High

841555

ACD10
Acyl-CoA dehydrogenase family member 10

1

4

High-throughput

0.489

High

841564

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

1

High-throughput

0.489

High

841568

VWDE
von Willebrand factor D and EGF domain-containing protein

1

6

High-throughput

0.489

High

841582

SPNS1
Protein spinster homolog 1

1

2

High-throughput

0.489

High

841585

ESRP2
Epithelial splicing regulatory protein 2

1

6

High-throughput

0.489

High

841594

FBX2
F-box only protein 2

1

10

High-throughput

0.489

High

841595

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

1

High-throughput

0.489

High

841596

DD19B
ATP-dependent RNA helicase DDX19B

1

4

High-throughput

0.489

High

841600

DJC16
DnaJ homolog subfamily C member 16

1

6

High-throughput

0.489

High

841603

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.489

High

366476

UROK
Urokinase-type plasminogen activator

1

5

High-throughput

0.445

High

841540

CNTP1
Contactin-associated protein 1

1

5

High-throughput

0.445

High

841547

SEM3A
Semaphorin-3A

1

3

High-throughput

0.445

High

841560

PCD23
Protocadherin-23

1

5

High-throughput

0.445

High

841602

PCDBB
Protocadherin beta-11

1

17

High-throughput

0.445

High

138004

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

High-throughput

0.437

High

603758

ITA2
Integrin alpha-2

1

0

High-throughput

0.426

High

841590

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.426

High

551771

CO6A1

1

2

High-throughput

0.407

High

551841

CO6A2

1

2

High-throughput

0.407

High

841532

PRELP
Prolargin

1

4

High-throughput

0.407

High

841534

LOXL3
Lysyl oxidase homolog 3

1

1

High-throughput

0.407

High

841574

PCD16
Protocadherin-16

1

13

High-throughput

0.407

High

841580

C1QT2
Complement C1q tumor necrosis factor-related protein 2

1

6

High-throughput

0.407

High

841589

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.407

High

841593

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

3

High-throughput

0.407

High

841566

TRM44
Probable tRNA

3

0

High-throughput

0.347

High

841572

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.318

High

841536

NPC2
NPC intracellular cholesterol transporter 2

2

0

High-throughput

0.313

High

841537

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.282

High

296100

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.279

Low

663349

KTHY
Thymidylate kinase

1

0

High-throughput

0.279

Low

777255

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.279

Low

841531

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

841535

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

841551

OZF
Zinc finger protein OZF

1

0

High-throughput

0.279

Low

841556

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.279

Low

841567

TRM2A
tRNA

1

0

High-throughput

0.279

Low

841581

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

841591

CHPF2
Chondroitin sulfate glucuronyltransferase

1

0

High-throughput

0.279

Low

219067

RA51C
DNA repair protein RAD51 homolog 3

1

0

High-throughput

0.249

Low

841573

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.249

Low

841562

GALT7
N-acetylgalactosaminyltransferase 7

1

0

High-throughput

0.232

Low

841563

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025