HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	17955473
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 451
+	Hs
		842847 CDN2A_HUMAN (1-156): 9.11e-52: 163: 100.00		TBA1C_HUMAN (1-451): 0: 722: 98.00
+	Hs
		457288 CDN2A_HUMAN (1-156): 9.11e-52: 163: 100.00		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		842722 CDN2A_HUMAN (1-156): 9.11e-52: 163: 100.00		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		943904 RIPK4_HUMAN (7-107): 5.52e-26: 104: 22.55		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		996811 EHMT2_HUMAN (59-152): 1.32e-20: 89.2: 27.37		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457336 RIPK4_HUMAN (7-107): 5.52e-26: 104: 22.55		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		943905 RIPK4_HUMAN (7-107): 5.52e-26: 104: 22.55		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		1030665 ANK2_HUMAN (3-63): 3.65e-14: 70.7: 24.19		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		1247490 POTEE_HUMAN (82-149): 2.13e-10: 59.6: 21.13		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		457372 ANK2_HUMAN (3-63): 3.65e-14: 70.7: 24.19		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		920425 DAPK1_HUMAN (69-155): 1.65e-14: 71.5: 24.14		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		62887 POTEF_HUMAN (82-149): 1.91e-10: 60: 21.13		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		62934 POTEF_HUMAN (82-149): 1.91e-10: 60: 21.13		TBB4B_HUMAN (1-437): 0: 694: 40.50