HitPredict

Interactor 1: GHR1 (C0LGQ9)
LRR receptor-like serine/threonine-protein kinase GHR1 (EC 2.7.11.1) (Protein GUARD CELL HYDROGEN PEROXIDE-RESISTANT 1) (AtGHR1) (Protein RADICAL-INDUCED CELL DEATH 7)
Gene: GHR1

Interactor 2: IOS1 (Q9C8I6)
LRR receptor-like serine/threonine-protein kinase IOS1 (EC 2.7.11.-) (Protein IMPAIRED OOMYCETE SUSCEPTIBILITY 1)
Gene: IOS1

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29320478, 30806640
Identification Methods	pull down, solid phase assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8, LRR_8~LRRNT_2, LRR_8~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0009738 - abscisic acid-activated signaling pathway GO:0016310 - phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1053 At			1 894
+	At
		84569 GHR1_ARATH (1-1053): 0: 802: 100.00		Y5596_ARATH (19-894): 0: 865: 47.56
+	At
		84512 GHR1_ARATH (1-1053): 0: 802: 100.00		Y4245_ARATH (1-894): 0: 855: 47.11
+	At
		84128 GHR1_ARATH (1-1053): 0: 802: 100.00		Y2289_ARATH (4-894): 0: 851: 45.26
+	At
		84537 Y1723_ARATH (2-1052): 0: 766: 26.48		Y4245_ARATH (1-894): 0: 855: 47.11
+	At
		84193 Y1723_ARATH (2-1052): 0: 766: 26.48		Y2289_ARATH (4-894): 0: 851: 45.26
+	At
		84926 Y1723_ARATH (2-1052): 0: 766: 26.48		Y5169_ARATH (1-878): 0: 851: 45.35
+	At
		84546 GHR1_ARATH (1-1053): 0: 802: 100.00		F4IB60_ARATH (1-894): 0: 794: 41.69
+	At
		4561 GHR1_ARATH (1-1053): 0: 802: 100.00		A0A178WLG7_ARATH (1-894): 0: 784: 40.28
+	At
		83374 GHR1_ARATH (1-1053): 0: 802: 100.00		Y1570_ARATH (7-863): 0: 767: 43.60
+	At
		96075 Y1723_ARATH (2-1052): 0: 766: 26.48		F4IB60_ARATH (1-894): 0: 794: 41.69
+	At
		4589 Y1723_ARATH (2-1052): 0: 766: 26.48		A0A178WLG7_ARATH (1-894): 0: 784: 40.28
+	At
		84294 Y1723_ARATH (2-1052): 0: 766: 26.48		C0LGM1_ARATH (18-864): 0: 708: 30.17
+	At
		84544 GHR1_ARATH (1-1053): 0: 802: 100.00		Y5487_ARATH (7-863): 0: 596: 27.53
+	At
		85101 Y1723_ARATH (2-1052): 0: 766: 26.48		Y5487_ARATH (7-863): 0: 596: 27.53
+	At
		84543 GHR1_ARATH (1-1053): 0: 802: 100.00		Y5457_ARATH (354-888): 7.57e-171: 511: 28.91
+	At
		84558 GHR1_ARATH (1-1053): 0: 802: 100.00		Y5371_ARATH (348-888): 8.36e-157: 475: 27.54
+	At
		84579 GHR1_ARATH (1-1053): 0: 802: 100.00		SERK4_ARATH (365-855): 1.44e-156: 474: 29.30
+	At
		84447 GHR1_ARATH (1-1053): 0: 802: 100.00		GSO1_ARATH (210-528): 5.76e-46: 181: 14.50
+	At
		84560 GHR1_ARATH (1-1053): 0: 802: 100.00		SERK1_ARATH (226-407): 2.2e-16: 85.8: 10.66
+	At
		84561 GHR1_ARATH (1-1053): 0: 802: 100.00		BAK1_ARATH (262-406): 7.19e-13: 74.2: 8.28