HitPredict

Interactor 1: RAB13 (P51153)
Ras-related protein Rab-13 (Cell growth-inhibiting gene 4 protein)
Gene: RAB13

Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21378754
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005802 - trans-Golgi network GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 203 Hs			1 901
+	Hs
		918850 RAB1A_HUMAN (1-200): 7.63e-89: 261: 50.50		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		968218 RAB1B_HUMAN (1-200): 3.52e-88: 259: 51.50		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		968196 RAB1C_HUMAN (1-200): 2.42e-85: 252: 50.00		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		894724 RAB8A_HUMAN (1-199): 2.51e-83: 247: 62.31		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		914016 RB11A_HUMAN (4-201): 6.63e-82: 243: 39.42		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Rn
		1157320 RAB1A_RAT (1-200): 7.63e-89: 261: 50.50		R9PXS2_RAT (14-901): 0: 1038: 93.81
+	Rn
		722753 RAB8A_RAT (1-202): 4.87e-84: 249: 62.14		R9PXS2_RAT (14-901): 0: 1038: 93.81
+	Hs
		685333 RAB8A_HUMAN (1-199): 2.51e-83: 247: 62.31		I5P2_HUMAN (143-897): 0: 719: 50.27
+	Dm
		185463 O18332_DROME (2-200): 5.25e-84: 248: 50.25		O46094_DROME (209-900): 1.12e-177: 537: 33.15