HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~HSA, Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1647 Hs			1 418
+	Hs
		846910 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		846917 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		846919 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		846918 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Mm
		929785 SMCA4_MOUSE (1-1647): 0: 1069: 96.66		ACTG_MOUSE (1-414): 0: 538: 35.42
+	Hs
		846733 SMCA2_HUMAN (1-1647): 0: 980: 71.69		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Xl
		292752 Q4VQ79_XENLA (1-1647): 0: 1017: 86.84		ACTB_XENLA (1-414): 0: 538: 35.66
+	Mm
		929795 SMCA2_MOUSE (40-1647): 0: 986: 72.73		ACTG_MOUSE (1-414): 0: 538: 35.42
+	Hs
		846742 SMCA2_HUMAN (1-1647): 0: 980: 71.69		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Dm
		501486 BRM_DROME (211-1642): 0: 858: 53.26		ACT1_DROME (3-414): 0: 534: 35.35
+	Dm
		361138 BRM_DROME (211-1642): 0: 858: 53.26		ACT2_DROME (3-414): 0: 532: 35.11
+	Hs
		229358 SMCA5_HUMAN (626-1631): 0: 835: 27.41		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Zm
		13638 A0A1D6MT91_MAIZE (651-1640): 0: 759: 27.37		A0A1D6FW13_MAIZE (2-414): 0: 526: 35.02
+	Hs
		891769 CHD4_HUMAN (482-1630): 0: 722: 23.79		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		891731 CHD3_HUMAN (300-1646): 0: 711: 20.80		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		929837 CHD3_HUMAN (300-1646): 0: 711: 20.80		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		932158 CHD4_HUMAN (482-1630): 0: 722: 23.79		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		932125 CHD3_HUMAN (300-1646): 0: 711: 20.80		ACTC_HUMAN (3-414): 0: 527: 35.59