Protein: ETV4
ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F) (Polyomavirus enhancer activator 3 homolog) (Protein PEA3)

Gene: ETV4
Organism: Homo sapiens
Interactions: 66
UniProt ID: P43268

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

846923

COP1
E3 ubiquitin-protein ligase COP1

6

19

Small-scale

0.730

High

846896

ERF
ETS domain-containing transcription factor ERF

1

16

High-throughput

0.665

High

846912

STK11
Serine/threonine-protein kinase STK11

2

1

Small-scale

0.631

High

846900

FLI1
Friend leukemia integration 1 transcription factor

1

17

High-throughput

0.618

High

846906

SMAD4
Mothers against decapentaplegic homolog 4

2

4

High-throughput

0.606

High

846913

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.603

High

846911

SMAD2
Mothers against decapentaplegic homolog 2

1

4

Small-scale

0.552

High

478284

HXD4
Homeobox protein Hox-D4

1

5

High-throughput

0.541

High

846898

ATX1
Ataxin-1

1

9

High-throughput

0.541

High

846915

HIF1A
Hypoxia-inducible factor 1-alpha

1

16

Small-scale

0.527

High

843358

HD
Huntingtin

1

0

High-throughput

0.518

High

846919

CARM1
Histone-arginine methyltransferase CARM1

1

3

High-throughput

0.515

High

846916

Q6FHY5
MEOX2 protein

1

16

High-throughput

0.515

High

421670

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

846929

EPAS1
Endothelial PAS domain-containing protein 1

1

16

Small-scale

0.501

High

300953

RL1D1
Ribosomal L1 domain-containing protein 1

1

2

High-throughput

0.500

High

846894

NOP2
28S rRNA

1

2

High-throughput

0.500

High

846903

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.500

High

846914

DDB1
DNA damage-binding protein 1

1

4

High-throughput

0.500

High

846918

DET1
DET1 homolog

1

3

High-throughput

0.500

High

846933

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

12

High-throughput

0.500

High

429471

JUN
Transcription factor Jun

1

17

Small-scale

0.481

High

846895

MEOX2
Homeobox protein MOX-2

1

17

High-throughput

0.481

High

846939

SAE1
SUMO-activating enzyme subunit 1

1

0

Small-scale

0.480

High

846940

SAE2
SUMO-activating enzyme subunit 2

1

0

Small-scale

0.480

High

138977

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

154643

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

161428

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

174323

ZN609
Zinc finger protein 609

1

14

High-throughput

0.479

High

180741

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

194522

KDM6A
Lysine-specific demethylase 6A

1

8

High-throughput

0.479

High

846897

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

18

High-throughput

0.479

High

846899

TFAM
Transcription factor A, mitochondrial

1

15

High-throughput

0.479

High

846901

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

846902

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

846905

SKP2
S-phase kinase-associated protein 2

1

10

Small-scale

0.479

High

846908

SSXT
Protein SSXT

1

20

High-throughput

0.479

High

846910

NCOA2
Nuclear receptor coactivator 2

1

20

High-throughput

0.479

High

846917

PAXI1
PAX-interacting protein 1

1

15

High-throughput

0.479

High

846920

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

18

High-throughput

0.479

High

846921

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

846922

KDM2B
Lysine-specific demethylase 2B

1

15

High-throughput

0.479

High

846924

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

846925

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

846926

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

846927

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

846928

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

20

High-throughput

0.479

High

846931

PYGO2
Pygopus homolog 2

1

1

High-throughput

0.479

High

846932

PCGF1
Polycomb group RING finger protein 1

1

14

High-throughput

0.479

High

846934

PDIP3
Polymerase delta-interacting protein 3

1

1

High-throughput

0.479

High

846935

P63
Tumor protein 63

1

5

Small-scale

0.479

High

846936

GRPE1
GrpE protein homolog 1, mitochondrial

1

7

High-throughput

0.479

High

846937

M1IP1
Mid1-interacting protein 1

1

1

High-throughput

0.479

High

846941

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

15

High-throughput

0.479

High

846942

PRR12
Proline-rich protein 12

1

19

High-throughput

0.479

High

846944

NCOR2
Nuclear receptor corepressor 2

1

12

High-throughput

0.479

High

846945

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.479

High

299100

FLOT1
Flotillin-1

1

10

High-throughput

0.457

High

846907

FLOT2
Flotillin-2

1

10

High-throughput

0.457

High

846938

SYLC
Leucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.457

High

174962

SC16A
Protein transport protein Sec16A

1

9

High-throughput

0.437

High

846904

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.437

High

846943

RM11
Large ribosomal subunit protein uL11m

1

1

High-throughput

0.437

High

846909

TAF7
Transcription initiation factor TFIID subunit 7

1

0

Small-scale

0.365

High

183605

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.249

Low

846930

CHOLN
Protein cholesin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025