HitPredict

Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: HIRA (P54198)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 1017
+	Hs
		848120 MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00		TBL1R_HUMAN (159-398): 4.63e-34: 140: 13.84
+	Hs
		328543 MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88		CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15
+	Hs
		245580 MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00		TBL1X_HUMAN (168-360): 7.84e-23: 106: 18.67
+	Hs
		1024603 MBD2_HUMAN (75-249): 3.32e-38: 146: 28.65		CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15
+	Mm
		1206590 MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44		TBL1R_MOUSE (205-397): 8.74e-17: 86.9: 16.41
+	Hs
		848145 MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00		NLE1_HUMAN (724-858): 6.84e-16: 83.8: 9.03
+	Hs
		1264784 TITIN_HUMAN (240-472): 1.28e-12: 72.8: 19.57		SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59