HitPredict

Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: DDX56 (Q9NY93)
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)
Gene: DDX56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 547
+	Mm
		1119394 MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44		DDX17_MOUSE (4-472): 5.22e-132: 400: 23.19
+	Mm
		1143002 MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44		DDX5_MOUSE (4-418): 5.74e-130: 394: 24.52
+	Mm
		1207272 MECP2_MOUSE (1-486): 5.34e-112: 341: 94.44		Q8BTS0_MOUSE (4-418): 1.72e-129: 393: 24.52
+	Hs
		848074 MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00		DDX42_HUMAN (5-463): 2.27e-120: 378: 25.49
+	Hs
		328489 MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		1264812 TITIN_HUMAN (240-472): 1.28e-12: 72.8: 19.57		DDX56_HUMAN (1-547): 3.44e-158: 464: 100.00
+	Hs
		1154074 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		DDX47_HUMAN (1-470): 7.93e-153: 447: 31.28
+	Hs
		1154061 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44