HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008540 - proteasome regulatory particle, base subcomplex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 418
+	Hs
		851400 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS6B_HUMAN (1-418): 1.69e-140: 409: 100.00
+	Hs
		700 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PRS10_HUMAN (35-417): 8.58e-128: 376: 40.47
+	Hs
		699 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PRS8_HUMAN (24-418): 1.66e-125: 370: 41.27
+	Hs
		975490 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS10_HUMAN (35-417): 8.58e-128: 376: 40.47
+	Hs
		969030 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS8_HUMAN (24-418): 1.66e-125: 370: 41.27
+	Hs
		968792 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS4_HUMAN (39-412): 4e-121: 360: 49.73
+	At
		235425 PSD1A_ARATH (1-911): 0: 1154: 46.61		PRS4A_ARATH (8-412): 7.27e-137: 401: 47.43
+	At
		1444857 PSD1B_ARATH (1-911): 0: 1140: 46.50		PRS4A_ARATH (8-412): 7.27e-137: 401: 47.43
+	Dm
		1464086 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9V405_DROME (4-418): 1.44e-131: 386: 86.27
+	Dm
		874996 PSMD1_DROME (2-894): 0: 1056: 58.84		PRS4_DROME (46-412): 2.7e-128: 379: 50.54
+	Dm
		198065 PSMD1_DROME (2-894): 0: 1056: 58.84		PRS8_DROME (40-418): 2.08e-128: 377: 41.95
+	Dm
		1464104 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9W414_DROME (28-417): 3.73e-125: 369: 41.94
+	Sp
		268014 RPN2_SCHPO (1-914): 0: 973: 42.15		PRS6B_SCHPO (34-418): 3.3e-138: 402: 73.90
+	Sp
		268018 RPN2_SCHPO (1-914): 0: 973: 42.15		PRS4_SCHPO (43-411): 5.19e-123: 365: 52.41
+	Sc
		740172 RPN2_YEAST (2-914): 0: 919: 38.04		PRS4_YEAST (34-414): 2.93e-124: 368: 50.38
+	Sc
		740197 RPN2_YEAST (2-914): 0: 919: 38.04		PRS10_YEAST (9-418): 1.83e-122: 364: 40.05
+	Sc
		740129 RPN2_YEAST (2-914): 0: 919: 38.04		PRS6B_YEAST (1-418): 3.06e-121: 360: 66.12
+	Hs
		69435 PSMD2_HUMAN (8-712): 0: 704: 20.00		A8K2M0_HUMAN (1-418): 1.69e-140: 409: 100.00
+	Hs
		851303 PSMD2_HUMAN (8-712): 0: 704: 20.00		PRS6B_HUMAN (1-418): 1.69e-140: 409: 100.00
+	Hs
		968692 PSMD2_HUMAN (8-712): 0: 704: 20.00		PRS4_HUMAN (39-412): 4e-121: 360: 49.73