HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008540 - proteasome regulatory particle, base subcomplex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 406
+	Hs
		907132 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	At
		221383 PSD1A_ARATH (1-911): 0: 1154: 46.61		PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62
+	Hs
		906907 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31
+	Hs
		693 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	At
		1341469 PSD1B_ARATH (1-911): 0: 1140: 46.50		PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62
+	Hs
		692 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Hs
		798739 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Hs
		730338 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Dm
		820502 PSMD1_DROME (2-894): 0: 1056: 58.84		PRS4_DROME (4-396): 3.02e-138: 403: 45.04
+	Dm
		1359001 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9V405_DROME (7-399): 9.79e-122: 360: 41.73
+	Dm
		1181026 PSMD1_DROME (2-894): 0: 1056: 58.84		Q7KMQ0_DROME (81-392): 1.77e-115: 345: 55.45
+	Sp
		251845 RPN2_SCHPO (1-914): 0: 973: 42.15		PRS8_SCHPO (7-406): 1.31e-122: 362: 76.81
+	Hs
		701 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64
+	Hs
		913340 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64
+	Sc
		693271 RPN2_YEAST (2-914): 0: 919: 38.04		PRS7_YEAST (84-391): 1.53e-111: 336: 54.87
+	Dm
		186132 PSMD1_DROME (2-894): 0: 1056: 58.84		PRS8_DROME (8-123): 6.29e-11: 65.5: 7.76
+	Dm
		1359019 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9W414_DROME (8-101): 2.04e-10: 64: 10.64
+	Hs
		66339 PSMD2_HUMAN (8-712): 0: 704: 20.00		A8K2M0_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Hs
		730247 PSMD2_HUMAN (8-712): 0: 704: 20.00		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31
+	Sc
		693349 RPN2_YEAST (2-914): 0: 919: 38.04		PRS8_YEAST (8-110): 1.31e-09: 61.7: 7.77