HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.984

Property	Details
Experiments	26157143, 24981860, 35575683, 39358380, 20871592, 16687578, 20011120, 19783980, 25281560, 26527279, 28514442, 34079125, 33961781, 34786730, 36089195, 16622419, 19498464, 16415788
Identification Methods	affinity chromatography technology, cross-linking study, pull down, unspecified method, proximity labelling technology, anti tag coimmunoprecipitation, protein array
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Chromo~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 136
+	Hs
		853278 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Hs
		853226 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Hs
		853316 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Mm
		1016758 CBX5_MOUSE (1-191): 1.91e-68: 208: 97.91		H32_MOUSE (1-136): 3.8e-61: 186: 99.27
+	Mm
		1017356 CBX5_MOUSE (1-191): 1.91e-68: 208: 97.91		H33_MOUSE (1-136): 1.45e-61: 186: 96.32
+	Hs
		853304 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		H3C_HUMAN (1-136): 8.62e-59: 179: 93.38
+	Hs
		998274 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Hs
		1097314 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Mm
		1016771 Q9DCC5_MOUSE (1-181): 3.08e-62: 192: 60.22		H32_MOUSE (1-136): 3.8e-61: 186: 99.27
+	Hs
		1016822 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Mm
		1017378 Q9DCC5_MOUSE (1-181): 3.08e-62: 192: 60.22		H33_MOUSE (1-136): 1.45e-61: 186: 96.32
+	Hs
		1097377 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Hs
		998210 CBX1_HUMAN (26-180): 2.33e-55: 175: 60.65		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Mm
		999019 CBX1_MOUSE (26-180): 2.33e-55: 175: 60.65		H31_MOUSE (1-136): 1.85e-62: 189: 100.00
+	Hs
		1014111 CBX1_HUMAN (26-180): 2.33e-55: 175: 60.65		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Dm
		381747 Q9W396_DROME (19-175): 3.88e-55: 176: 50.96		H3_DROME (1-136): 3.8e-61: 186: 99.27
+	Hs
		1014069 CBX1_HUMAN (26-180): 2.33e-55: 175: 60.65		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Hs
		1014137 CBX1_HUMAN (26-180): 2.33e-55: 175: 60.65		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Hs
		853196 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		CENPA_HUMAN (9-133): 7.51e-45: 144: 50.00
+	Hs
		883528 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		CENPA_HUMAN (9-133): 7.51e-45: 144: 50.00