HitPredict

Interactor 1: POLO (P52304)
Serine/threonine-protein kinase polo (EC 2.7.11.21)
Gene: POLO

Interactor 2: POLO (P52304)
Serine/threonine-protein kinase polo (EC 2.7.11.21)
Gene: POLO

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 23857770, 29167465
Identification Methods enzymatic study, affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, POLO_box~POLO_box
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0000915 - actomyosin contractile ring assembly
GO:0000922 - spindle pole
GO:0000940 - outer kinetochore
and 35 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 576
Dm

1 576
+ Dr
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Sc
+ Hs
+ Gm
+ At
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024