Protein: ARHGI
Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)

Gene: ARHGI, ARHGEF18
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q6ZSZ5

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007264 - small GTPase-mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1254212

ARG28
Rho guanine nucleotide exchange factor 28

2

17

High-throughput

0.767

High

962190

RHOA
Transforming protein RhoA

2

20

Small-scale

0.755

High

978103

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

787559

TNR3
Tumor necrosis factor receptor superfamily member 3

3

1

High-throughput

0.667

High

1086368

AKP13
A-kinase anchor protein 13

1

18

High-throughput

0.665

High

374702

RASH
GTPase HRas

1

14

Small-scale

0.647

High

1254209

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1254215

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

644518

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

2

0

High-throughput

0.559

High

990387

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1254217

VAPA
Vesicle-associated membrane protein-associated protein A

1

5

High-throughput

0.536

High

1038890

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

0

High-throughput

0.513

High

1146238

ZMY11
Zinc finger MYND domain-containing protein 11

1

4

High-throughput

0.501

High

854127

KI67
Proliferation marker protein Ki-67

1

6

High-throughput

0.489

High

323446

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

660103

COF1
Cofilin-1

1

2

High-throughput

0.479

High

983514

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

16

Small-scale

0.479

High

1007099

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.479

High

1107851

SQSTM
Sequestosome-1

1

6

High-throughput

0.479

High

1254210

CNTRL
Centriolin

1

12

High-throughput

0.479

High

1254213

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1254218

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

868542

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

1254216

E41L5
Band 4.1-like protein 5

1

9

High-throughput

0.445

High

928482

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.437

High

1091628

TAF10
Transcription initiation factor TFIID subunit 10

1

2

High-throughput

0.437

High

1254214

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

10

High-throughput

0.437

High

1254211

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.426

High

1199879

AKIR2
Akirin-2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025