HitPredict

Interactor 1: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1124 Hs			1 2752
+	Hs
		238439 JAK2_HUMAN (7-1101): 0: 889: 47.80		MUC5B_HUMAN (601-2752): 1.13e-58: 228: 9.90
+	Hs
		434084 LYN_HUMAN (781-1110): 2.14e-92: 307: 28.40		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		339147 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		523118 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1071005 ERBB4_HUMAN (822-1104): 2.36e-87: 310: 36.62		MUC4_HUMAN (1029-2712): 5.23e-22: 107: 13.82
+	Hs
		616857 JAK1_HUMAN (761-1119): 1.21e-38: 158: 18.62		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		152571 ABL1_HUMAN (760-1102): 3.81e-95: 330: 29.48		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		297808 LYN_HUMAN (781-1110): 2.14e-92: 307: 28.40		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		433701 LYN_HUMAN (781-1110): 2.14e-92: 307: 28.40		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		782820 CSK_HUMAN (521-787): 4.41e-17: 87.4: 27.01		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		338874 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		338765 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		MUC16_HUMAN (111-2747): 6.13e-36: 153: 10.09
+	Hs
		338965 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50
+	Hs
		338878 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		MUC4_HUMAN (1029-2712): 5.23e-22: 107: 13.82
+	Hs
		338769 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Mm
		222869 ACK1_MOUSE (525-790): 6.57e-16: 85.1: 29.54		ANK2_MOUSE (875-2680): 3.07e-20: 101: 14.69
+	Hs
		383946 ERBB2_HUMAN (527-780): 1.84e-13: 77.4: 25.00		MUC4_HUMAN (1029-2712): 5.23e-22: 107: 13.82
+	Hs
		338292 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23