HitPredict

Interactor 1: UBCD2 (P52485)
Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: Ubc2

Interactor 2: Q9VNJ0 (Q9VNJ0)
Degringolade, isoform A (GM01182p)
Gene: dgrn

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Dm			1 319
+	Dm
		854561 UBCD2_DROME (1-232): 2.16e-92: 272: 100.00		Q8I0J6_DROME (1-319): 1.61e-79: 246: 93.10
+	Hs
		256237 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		BRE1B_HUMAN (32-319): 8.58e-64: 219: 17.86
+	Hs
		919748 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		BRE1A_HUMAN (32-319): 1.67e-52: 187: 14.94
+	Ce
		712245 UBC2_CAEEL (87-231): 6.7e-81: 240: 66.21		BRE1_CAEEL (60-319): 5.14e-40: 151: 19.22
+	Hs
		919705 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RNF4_HUMAN (161-319): 1.73e-29: 113: 26.98
+	Hs
		941604 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RNF4_HUMAN (161-319): 1.73e-29: 113: 26.98
+	Hs
		941319 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		RNF4_HUMAN (161-319): 1.73e-29: 113: 26.98
+	Dm
		854562 UBCD2_DROME (1-232): 2.16e-92: 272: 100.00		Q8IR26_DROME (243-318): 1.79e-12: 68.5: 22.79
+	Dm
		854578 UBCD2_DROME (1-232): 2.16e-92: 272: 100.00		Q9VXP1_DROME (243-318): 1.69e-12: 68.5: 22.79
+	Hs
		1290204 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RN125_HUMAN (235-309): 3.24e-16: 78.1: 28.95
+	Hs
		919821 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN125_HUMAN (235-309): 3.24e-16: 78.1: 28.95
+	Hs
		1290196 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		RN125_HUMAN (235-309): 3.24e-16: 78.1: 28.95
+	Hs
		919794 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		COP1_HUMAN (258-306): 8.29e-14: 73.9: 40.82
+	Hs
		1246146 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		COP1_HUMAN (258-306): 8.29e-14: 73.9: 40.82
+	Hs
		1292368 UB2D4_HUMAN (87-231): 1.43e-81: 241: 64.83		RN185_HUMAN (263-318): 5.11e-13: 68.5: 25.42
+	Hs
		919826 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RN185_HUMAN (263-318): 5.11e-13: 68.5: 25.42
+	Dm
		1215059 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q8IR26_DROME (243-318): 1.79e-12: 68.5: 22.79
+	Dm
		1337333 Q9I7T6_DROME (2-231): 4.62e-78: 240: 40.34		Q9VXP1_DROME (243-318): 1.69e-12: 68.5: 22.79
+	Hs
		282607 UB2D2_HUMAN (87-231): 3.29e-81: 241: 65.52		RNF8_HUMAN (92-314): 9.22e-12: 67.3: 14.41
+	Hs
		282716 UB2E2_HUMAN (37-232): 9.36e-80: 239: 72.50		RNF8_HUMAN (92-314): 9.22e-12: 67.3: 14.41