Protein: S15A1
Solute carrier family 15 member 1 (Intestinal H(+)/peptide cotransporter) (Oligopeptide transporter, small intestine isoform) (Peptide transporter 1)

Gene: S15A1, SLC15A1
Organism: Homo sapiens
Interactions: 109
UniProt ID: P46059

Gene Ontology (top 5):
GO:0005427 - proton-dependent oligopeptide secondary active transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0005903 - brush border
GO:0006811 - monoatomic ion transport
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

72868

HACD1
Very-long-chain

2

2

High-throughput

0.628

High

630468

RAB3B
Ras-related protein Rab-3B

2

3

High-throughput

0.628

High

755330

ABCD1
ATP-binding cassette sub-family D member 1

2

5

High-throughput

0.628

High

854521

AT12A
Potassium-transporting ATPase alpha chain 2

2

5

High-throughput

0.628

High

854525

ARF5
ADP-ribosylation factor 5

2

2

High-throughput

0.628

High

854528

MTX1
Metaxin-1

2

1

High-throughput

0.628

High

854534

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

2

1

High-throughput

0.628

High

854536

MTX3
Metaxin-3

2

1

High-throughput

0.628

High

854539

RIF1
Telomere-associated protein RIF1

2

2

High-throughput

0.628

High

854542

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

2

3

High-throughput

0.628

High

854545

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

2

1

High-throughput

0.628

High

854555

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

4

High-throughput

0.628

High

854557

SPPL3
Signal peptide peptidase-like 3

2

1

High-throughput

0.628

High

854568

RB39B
Ras-related protein Rab-39B

2

4

High-throughput

0.628

High

854590

MITOS
Mitochondrial potassium channel ATP-binding subunit

2

1

High-throughput

0.628

High

249442

ACSL4
Long-chain-fatty-acid--CoA ligase 4

2

0

High-throughput

0.602

High

501803

CO4A
Complement C4-A

2

0

High-throughput

0.602

High

658657

JAK1
Tyrosine-protein kinase JAK1

2

0

High-throughput

0.602

High

854520

KNTC1
Kinetochore-associated protein 1

2

0

High-throughput

0.602

High

854569

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

2

0

High-throughput

0.602

High

854586

PXMP2
Peroxisomal membrane protein 2

2

0

High-throughput

0.602

High

854593

S53A1
Solute carrier family 53 member 1

2

0

High-throughput

0.602

High

122598

UBXN8
UBX domain-containing protein 8

2

3

High-throughput

0.574

High

854523

TBA4A
Tubulin alpha-4A chain

2

3

High-throughput

0.574

High

854526

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

2

1

High-throughput

0.574

High

854529

STAR3
StAR-related lipid transfer protein 3

2

2

High-throughput

0.574

High

854541

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

2

4

High-throughput

0.574

High

854548

ADCK1
AarF domain-containing protein kinase 1

2

2

High-throughput

0.574

High

854558

SFXN5
Sideroflexin-5

2

1

High-throughput

0.574

High

854564

MFRN2
Mitoferrin-2

2

5

High-throughput

0.574

High

854571

OMA1
Metalloendopeptidase OMA1, mitochondrial

2

1

High-throughput

0.574

High

854572

TV23C
Golgi apparatus membrane protein TVP23 homolog C

2

1

High-throughput

0.574

High

854576

SFXN3
Sideroflexin-3

2

1

High-throughput

0.574

High

854589

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

3

High-throughput

0.574

High

854596

IPO11
Importin-11

2

9

High-throughput

0.574

High

854598

CDYL
Chromodomain Y-like protein

2

2

High-throughput

0.574

High

170491

RAB7L
Ras-related protein Rab-7L1

1

7

High-throughput

0.536

High

270627

ATP9A
Probable phospholipid-transporting ATPase IIA

1

8

High-throughput

0.536

High

565575

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

7

High-throughput

0.536

High

630403

RAB3A
Ras-related protein Rab-3A

1

3

High-throughput

0.536

High

854524

PRKDC
DNA-dependent protein kinase catalytic subunit

1

4

High-throughput

0.536

High

854531

RHEB
GTP-binding protein Rheb

1

4

High-throughput

0.536

High

854554

ATLA2
Atlastin-2

1

1

High-throughput

0.536

High

854556

S35G2
Solute carrier family 35 member G2

1

4

High-throughput

0.536

High

854560

YLAT2
Y+L amino acid transporter 2

1

4

High-throughput

0.536

High

854577

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

1

High-throughput

0.536

High

854584

RAB18
Ras-related protein Rab-18

1

6

High-throughput

0.536

High

854591

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

1

High-throughput

0.536

High

271681

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

854533

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.513

High

854538

TM164
Transmembrane protein 164

1

0

High-throughput

0.513

High

854559

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

854567

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.513

High

854578

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

854580

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

854543

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

1

High-throughput

0.489

High

854551

RDH13
Retinol dehydrogenase 13

1

2

High-throughput

0.489

High

375270

RASK
GTPase KRas

1

6

High-throughput

0.479

High

854562

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

0.457

High

564806

NCAM1
Neural cell adhesion molecule 1

1

3

High-throughput

0.445

High

854540

CARL1
F-actin-uncapping protein LRRC16A

1

2

High-throughput

0.445

High

854575

IPO9
Importin-9

1

9

High-throughput

0.445

High

854537

NU188
Nucleoporin NUP188

1

0

High-throughput

0.426

High

854546

VP35L
VPS35 endosomal protein-sorting factor-like

1

0

High-throughput

0.426

High

854553

FAD1
FAD synthase

1

0

High-throughput

0.426

High

854561

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.426

High

854583

WDR6
tRNA

1

0

High-throughput

0.426

High

854585

RIC8A
Chaperone Ric-8A

1

0

High-throughput

0.426

High

854587

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.426

High

177820

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

2

High-throughput

0.407

High

854522

CANB1
Calcineurin subunit B type 1

1

7

High-throughput

0.407

High

854579

CLPB
Mitochondrial disaggregase

1

2

High-throughput

0.407

High

854592

LMCD1
LIM and cysteine-rich domains protein 1

1

2

High-throughput

0.407

High

854597

HACL1
2-hydroxyacyl-CoA lyase 1

1

2

High-throughput

0.407

High

66157

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

2

0

High-throughput

0.328

High

67362

RTL8C
Retrotransposon Gag-like protein 8C

2

0

High-throughput

0.328

High

173677

BTAF1
TATA-binding protein-associated factor 172

2

0

High-throughput

0.328

High

665076

COT2
COUP transcription factor 2

2

0

High-throughput

0.328

High

854544

MIC27
MICOS complex subunit MIC27

2

0

High-throughput

0.328

High

854549

DAAF5
Dynein axonemal assembly factor 5

2

0

High-throughput

0.328

High

854552

MCU
Calcium uniporter protein, mitochondrial

2

0

High-throughput

0.328

High

854566

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

2

0

High-throughput

0.328

High

854519

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

2

0

High-throughput

0.313

High

854582

OPA3
Optic atrophy 3 protein

2

0

High-throughput

0.313

High

129858

GET1
Guided entry of tail-anchored proteins factor 1

1

0

High-throughput

0.279

Low

360261

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.279

Low

854527

RN5A
2-5A-dependent ribonuclease

1

0

High-throughput

0.279

Low

854532

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

854565

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.279

Low

854570

RSPRY
RING finger and SPRY domain-containing protein 1

1

0

High-throughput

0.279

Low

854581

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

854588

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

854595

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low

612922

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

128837

MEN1
Menin

1

0

High-throughput

0.232

Low

244813

TYW4
tRNA wybutosine-synthesizing protein 4

1

0

High-throughput

0.232

Low

257538

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.232

Low

261710

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.232

Low

293345

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.232

Low

335608

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.232

Low

854530

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.232

Low

854535

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.232

Low

854547

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.232

Low

854550

CI040
Uncharacterized protein C9orf40

1

0

High-throughput

0.232

Low

854563

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.232

Low

854573

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.232

Low

854574

GUCD1
Protein GUCD1

1

0

High-throughput

0.232

Low

854594

MTFP1
Mitochondrial fission process protein 1

1

0

High-throughput

0.232

Low

854599

TPPC4
Trafficking protein particle complex subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025