HitPredict

Interactor 1: HMGA2 (P52926)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2

Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18425117
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010628 - positive regulation of gene expression GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0071141 - SMAD protein complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 109 Hs			1 465
+	Hs
		857502 HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00		SMAD5_HUMAN (2-465): 0: 619: 89.46
+	Hs
		171376 HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00		SMAD9_HUMAN (3-465): 0: 607: 81.29
+	Mm
		857640 HMGA2_MOUSE (1-109): 4.6e-41: 133: 95.41		SMAD2_MOUSE (3-465): 0: 543: 55.14