HitPredict

Interactor 1: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Interactor 2: CDK20 (Q8IZL9)
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)
Gene: CDK20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16954377
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 346
+	Hs
		625340 PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		625180 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		625300 PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		625299 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		414790 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18
+	Dm
		524602 PP12_DROME (209-479): 6.64e-158: 452: 38.97		CDK2_DROME (1-290): 2.59e-128: 371: 41.72
+	Mm
		926533 PP1G_MOUSE (196-488): 1.32e-154: 444: 36.88		CDK2_MOUSE (1-296): 4.07e-131: 379: 37.68
+	Hs
		414846 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18
+	Mm
		509478 PP1G_MOUSE (196-488): 1.32e-154: 444: 36.88		CDK1_MOUSE (1-292): 3.11e-130: 375: 42.52
+	Sp
		383446 PP11_SCHPO (200-481): 4.13e-152: 438: 39.93		CDK1_SCHPO (1-292): 4.02e-132: 380: 42.48
+	Hs
		905833 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		CDK5_HUMAN (1-294): 2.23e-128: 370: 45.09