Interactor 1: UFD1 (P53044)
Ubiquitin fusion degradation protein 1 (UB fusion protein 1) (Polymerase-interacting protein 3)
Gene: UFD1

Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 16179952, 25215493
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 361
Sc

1 551
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024